Whether you walk all day long, hike, run, or shoot hoops, blisters are almost as much a part of the action as sweat is--but they don't have to be. You can take measures to avoid them. And if you develop a blister, you have several options for lessening the pain and lowering your risk of infection. To prevent blisters, you need to minimize friction. For the feet, this begins with shoe selection. Shoes should fit comfortably, with about a thumb's width between your longest toe and the end of the shoe. Narrow shoes can cause blisters on the big toe and little toe. A shallow toe box can lead to blisters on the tops of the toes, while loose shoes can create blisters on the tips of the toes. Our Sole Defense Orthotic line contains X-Static which helps prevent hot spots and moisture build-up.